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March 2005

By Lawrence A. Schiffman, DO, and Stephen M. Schleicher, MD

CASE:

An 11-year-old girl presents with hair loss that has progressed for two years. Her medical history is negative for systemic disease, including thyroid abnormality. She comes from a broken home and is said to be under a lot of stress. Numerous treatments have been attempted in the past, but none has been effective. On physical exam, she appears generally healthy. The area of hair loss is a large triangular patch on the right parietal scalp, with no erythema or scale. Small, white, wispy hairs are present on the periphery of the bald area.

WHAT IS YOUR DIAGNOSIS?

 
 
 
 
The cause of alopecia areata (AA) is unknown, but it is thought to be immune-mediated. Some cases are related to thyroid dysfunction, and others are ascribed to stress. The condition becomes evident by age 20 in half of all cases and has no gender predilection. Most cases resolve on their own, but relapses are common. Treatment of smaller patches of AA usually entails both topical and intralesional steroids. Hairs may initially grow without pigment. Anthralin, imiquimod, and topical minoxidil have also been used, with variable success. This patient's condition continued to progress, eventually leading to complete loss of hair (alopecia totalis).


 

Dr. Schiffman is a fellow at DermDx Centers for Dermatology of Northeastern Pennsylvania, headquartered in Hazelton. Dr. Schleicher is director of DermDx Centers and a clinical instructor of dermatology at the Philadelphia College of Osteopathic Medicine, at Kings College in Wilkes-Barre, Pennsylvania, and at Arcadia University in Glenside, Pennsylvania. He is also a member of the EMERGENCY MEDICINE editorial board.

Emerg Med 37(3):31-32, 2005

 



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