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By Lawrence A. Schiffman, DO, and Stephen M. Schleicher, MD

CASE:

A 66-year-old woman presents with an enlarging lesion of her right axilla, which she believes to be a wart. She reports that it bled recently, prompting her to seek medical attention. The patient is a cigarette smoker with no history of skin cancer. Examination of the affected area reveals a 3- x 5-cm erythematous plaque with a hyperkeratotic, crusted core. Cervical and axillary nodes are not palpable.

WHAT IS YOUR DIAGNOSIS?

 
 
 
 
Cutaneous biopsy of this lesion revealed invasive squamous cell carcinoma. This second most prevalent form of skin cancer is rarely seen in sun-protected skin folds. Cigarette smoking is a risk factor. If left untreated, up to 20% of cases may metastasize. The uncommon location in this case illustrates the need for total body skin examination.


 

Dr. Schiffman is a fellow at DermDx Centers for Dermatology of Northeastern Pennsylvania, headquartered in Hazelton. Dr. Schleicher is director of DermDx Centers and a clinical instructor of dermatology at the Philadelphia College of Osteopathic Medicine, at Kings College in Wilkes-Barre, Pennsylvania, and at Arcadia University in Glenside, Pennsylvania. He is also a member of the EMERGENCY MEDICINE editorial board.

Emerg Med 37(6):37, 2005

 



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